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中年阿爾茲海默癥生物標(biāo)志物變化可預(yù)測老年癡呆發(fā)生
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CENPJ抗原;著絲粒蛋白J重組蛋白多種屬 該基因編碼一種屬于著絲粒蛋白家族的蛋白質(zhì)。在細(xì)胞分裂過程中,該蛋白在維持中心體完整性和正常紡錘體形態(tài)方面起著結(jié)構(gòu)作用,并參與中心體處的微管解體。該蛋白可以作為Stat5信號通路中的轉(zhuǎn)錄輔激活子,也可以作為NF-kappaB介導(dǎo)的轉(zhuǎn)錄的輔激活因子,可能是通過其與輔激活子p300/CREB結(jié)合蛋白的相互作用。該基因的突變與原發(fā)性常染色體隱性小頭畸形有關(guān),這是
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品牌 | 信裕生物 | CAS | 詳見說明書 |
---|---|---|---|
分子式 | 詳見說明書 | 純度 | > 95% |
分子量 | 27.2kDa | 貨號 | XY90915RPHu01 |
規(guī)格 | 50µg/100µg | 供貨周期 | 一周 |
主要用途 | SDS-PAGE; WB | 應(yīng)用領(lǐng)域 | 生物產(chǎn)業(yè) |
Recombinant Centromere Protein J (CENPJ)
著絲粒蛋白J(CENPJ)重組蛋白
[ PROPERTIES ]
Source:Prokaryotic expression
Host: E.coli
Residues: Met1~Asn207
Tags:N-terminal His Tag
Subcellular Location: Cytoplasm
Purity: > 95%
Traits:Freeze-dried powder
Buffer formulation: PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Original Concentration:200µg/mL
Applications:Positive Control; Immunogen; SDS-PAGE; WB.
(May be suitable for use in other assays to be determined by the end user.)
Predicted isoelectric point:5.6
Predicted Molecular Mass: 27.2kDa
Accurate Molecular Mass: 30kDa as determined by SDS-PAGE reducing conditions.
[ USAGE ]
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
[ STORAGE AND STABILITY ]
Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8oC for one month.
Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
[SEQUENCE ]
[ IDENTIFICATION ]
[ IMPORTANT NOTE ]
The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
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